#ALPHA FETOPROTEIN SERIAL#

Valores superiores a 1000 ng/ml son prácticamente indicativos de padecer carcinoma hepatocelular ( cáncer de hígado ). This article will review the history, biochemistry, and different assays of AFP in AF and blood as well as the indications and limitations for their use. Los niveles de la alfa-fetoproteína en sangre son excesivamente elevados y si no se debe a un embarazo la probabilidad de que se deba a un cáncer de hígado son muy elevadas. Tested in Western Blot (WB) and Immunocytochemistry (ICC/IF). It may be present in high levels in certain malignancies and has been useful in monitoring their recurrence. Invitrogen Anti-alpha-Fetoprotein Monoclonal (AFP3), eBioscience, Catalog 14-6583-82. Pregnancy is the only normal situation in which AFP is present after birth. This requires that a laboratory establish its normal range of MS/AFP levels between 15 and 20 weeks gestation, employ a reliable assay with adequate controls, and has recourse to genetic counseling as well as expert sonography, amniocentesis and amniography if necessary. Maternal serum (MS) AFP measurement can be used as a screening procedure to identify neural tube defects providing a rigorous protocol is followed. Alpha-fetoprotein (AFP) is an oncofetal glycoprotein that is expressed in yolk sac tumor and its variants, including hepatoid and endometrioid yolk sac tumor. In pregnancy increased levels have high sensitivity and low specificity for fetal. It is not normally found in healthy adults. Moderate increases may occur with non-malignant disease associated with liver cell regeneration. Alpha-fetoprotein (AFP) is a protein normally made by the liver and yolk sac of a developing baby. Excluding fetal blood contamination, elevated AF/AFP levels indicate fetal demise or one of several abnormalities. Hepatocellular carcinoma is usually associated with very high levels of -fetoprotein, but a normal level does not exclude this diagnosis, nor of germ cell tumour. A small amount crosses the membranes into the maternal circulation. It is produced by fetal liver and passes into the amniotic fluid (AF) via fetal urine.

#ALPHA FETOPROTEIN SERIAL#

If the patient is pregnant, include the approximate gestational age with the test request form and also order Alpha-Fetoprotein (AFP), Maternal Serum for Open Spina Bifida.Values obtained with different assay methodologies should not be used interchangeably in serial testing. Alpha fetoprotein (AFP) is the major protein of fetal serum and most resembles albumen, which replaces it shortly after birth. Additional Information: UFHPL Epic order code: LAB559 Special Instructions.